Proven GLP-1 Therapy for Effective Weight Loss
Compounded semaglutide with B₁₂, backed by landmark clinical trials showing up to 14.9% average weight loss. Prepared by a US-licensed 503A pharmacy and guided by your provider.
A GLP-1 receptor agonist that targets three key pathways to support sustainable weight loss
Activates GLP-1 receptors in the brain to reduce hunger signals and food-related thoughts, helping you feel satisfied with less food.
Delays gastric emptying to prolong the feeling of fullness after meals, naturally reducing caloric intake throughout the day.
Enhances glucose-dependent insulin secretion, helping stabilize blood sugar levels and reduce cravings for high-sugar foods.
A GLP-1 receptor agonist that targets three key pathways to support sustainable weight loss
Feature
Semaglutide
Tirzepatide
Mechanism
GLP-1
Dual GLP-1/GIP
Administration
Weekly
Weekly
Formulation
Compounded
Compounded
Starting Price
$147/mo
$249/mo
Best For
Value + Proven Results
Maximum Weight Loss
Clinically Proven
Backed by the STEP 1 trial with 1,961 participants showing significant, sustained weight loss results.
Appetite Control
Naturally reduces hunger and food-related thoughts so you feel satisfied with smaller portions.
Weekly Injection
Simple once-weekly subcutaneous injection that fits easily into your routine.
Metabolic Support
Helps regulate blood sugar and insulin sensitivity for comprehensive metabolic health.
Sustainable Results
Gradual dose escalation over 16+ weeks optimizes results while minimizing side effects.
Enhanced with B₁₂
Compounded with vitamin B₁₂ to support energy levels and overall wellness during treatment.
Your dose increases every 4 weeks over 16+ weeks to optimize results while minimizing side effects
1
0.25mg weekly
Starting dose — body begins adapting to the medication
5
0.5mg weekly
First therapeutic dose — noticeable appetite reduction
9
1.0mg weekly
Increased efficacy — weight loss accelerates
13
1.7mg weekly
Strong therapeutic effect — significant results visible
17
2.4mg weekly
Maximum dose — peak efficacy for weight loss
Compounded Semaglutide is a customized medication prepared by a state-licensed sterile compounding pharmacy pursuant to a prescription from a licensed healthcare provider. Some compounded formulations may include additional ingredients, such as vitamin B₁₂, based on provider discretion and patient needs.
Compounded medications are not FDA-approved, which means the FDA does not evaluate them for safety, effectiveness, or quality before they are dispensed.
Individual results vary significantly based on factors like starting weight, diet, exercise, adherence to treatment, and individual physiology. In the STEP 1 clinical trial, participants lost an average of 14.9% of their body weight over 68 weeks. Your provider will set realistic expectations during your consultation. No specific outcomes are guaranteed.
Semaglutide mimics the naturally occurring hormone GLP-1, which is released after eating. It works through three pathways: reducing appetite signals in the brain, slowing gastric emptying to prolong fullness, and enhancing glucose-dependent insulin secretion. This comprehensive approach helps reduce caloric intake naturally.
Compounded Semaglutide and compounded Tirzepatide are commonly chosen by patients seeking provider-guided support for appetite control, metabolic health, and sustainable weight management. Treatment recommendations are based on individual health history, goals, and provider evaluation.
The most common side effects are gastrointestinal: nausea, diarrhea, vomiting, constipation, and decreased appetite. These are typically mild-to-moderate and often diminish as your body adjusts. The gradual dose escalation protocol helps minimize these effects. Your provider will discuss all potential risks and monitor you throughout treatment.
Semaglutide is an excellent choice for patients seeking proven, cost-effective weight loss. At $147/month vs $249/month for Tirzepatide, it offers significant savings while still delivering clinically proven results. It's ideal for first-time GLP-1 users and those who want a well-established treatment with extensive clinical data.
